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Autologous Mesotherapy (PRP)

Autologous Mesotherapy (PRP): What Is It?

Autologous mesotherapy, also known as PRP (Platelet-Rich Plasma) therapy, is considered one of the most advanced and effective forms of mesotherapy available in aesthetic medicine.

It is a non-invasive, natural procedure that utilizes the patient’s own blood to extract plasma rich in platelets, which is then re-injected into specific areas of the face or body to promote regeneration and rejuvenation.

Platelets and plasma play a vital role in the body’s natural healing mechanisms by releasing growth factors and proteins that support cell regeneration and tissue repair. This treatment stimulates the body’s own production of collagen, elastin, and hyaluronic acid, helping to restore elasticity and smoothness to aging or damaged skin.

Where Is PRP Used?

PRP therapy is applied to various areas of the body, with the most common being:

  • The face (PRP facial)
  • The neck
  • Décolletage
  • Scalp (for hair restoration)

It is a popular choice for patients who want to improve skin texture, reduce fine lines, wrinkles, dark circles, and achieve a natural, radiant look—without foreign substances or surgery.

How Is the Treatment Performed?

  1. Topical anesthetic cream is applied for 45 minutes to numb the area.
  2. A small blood sample is drawn from the patient.
  3. The sample is processed in a centrifuge to separate the platelet-rich plasma.
  4. The PRP is injected into the treatment area using very fine needles.

The procedure is minimally painful, with almost no downtime. Patients can typically return to their daily routine immediately.

Since the treatment uses the patient’s own biological material, the risk of allergic reaction or complications is extremely low.

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How Many Sessions Are Needed?

The number of sessions depends on:

  • The treatment area
  • The severity of the skin concern
  • The desired results

Most patients require 4–6 sessions, spaced approximately one month apart. For maintenance, one session per year is typically recommended.

Duration per session:

  • Small areas: ~30 minutes
  • Larger areas: 45–60 minutes

PRP can be performed year-round, without restrictions due to sun exposure or seasonality.

Results of PRP Mesotherapy

Results vary from patient to patient based on individual skin condition and biological response. Generally:

  • Visible improvements appear after ~20 days
  • Results can last up to 12 months
  • Skin becomes smoother, firmer, more luminous
  • Wrinkles, fine lines, dark circles, and imperfections are reduced over time

The treatment provides gradual, natural rejuvenation—not an artificial or overdone look.

Cost of Autologous Mesotherapy

The price of PRP therapy varies depending on:

  • The area treated
  • The number of sessions required
  • The technique used
  • The patient’s individual needs

Choosing a qualified and experienced medical professional is essential to ensure safe, visible, and long-lasting results.

At KM Plastic Surgery Clinic, Dr. Konstantinos Makrygiorgis combines medical expertise, advanced equipment, and modern facilities to deliver natural, impressive, and medically safe results.

Plastic Surgeon Dr. Konstantinos Ch. Makrygiorgis

Plastic surgery is the perfect blend of science and art, of passion and technology. Our primary goal is to help you achieve your personal aesthetic aspirations, while also providing you with clear and honest guidance for your benefit. Perfectionists by nature, we are fully committed to your vision to how you imagine your best self. Because perfection is a deeply personal matter, and it doesn’t come in one single form.

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