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Fractional CO₂ Laser

What is Fractional CO₂ Laser?

Fractional CO₂ Laser is an advanced, targeted skin resurfacing treatment that uses carbon dioxide energy to improve the texture, tone and overall quality of the skin, while leaving surrounding tissue intact for faster healing and minimal downtime.

How does fractional technology work?


Unlike older laser systems that treated the entire surface uniformly, Fractional CO₂ creates microscopic columns of thermal stimulation in the deeper layers of the skin.
This activates regeneration mechanisms, helping to smooth acne scars, fine lines, uneven texture and signs of photoaging.

Where can it be applied?


In addition to the face, Fractional CO₂ Laser can be effectively used on the neck and décolleté, areas that commonly show signs of laxity, uneven tone or pigmentation.

Fractional Laser for the Face – What It Truly Improves

  • acne scars that require targeted improvement
  • stretch marks and demanding body areas
  • dark circles caused by texture irregularities
  • fine lines around the eyes and mouth
  • pigmentation issues & uneven skin tone

Plastic Surgeon Dr. Konstantinos Ch. Makrygiorgis

Plastic surgery is the perfect blend of science and art, of passion and technology. Our primary goal is to help you achieve your personal aesthetic aspirations, while also providing you with clear and honest guidance for your benefit. Perfectionists by nature, we are fully committed to your vision to how you imagine your best self. Because perfection is a deeply personal matter, and it doesn’t come in one single form.

Learn more about the Doctor

How Fractional CO₂ Laser Treatment Is Performed

Skin preparation

The session begins with thorough cleansing of the area and application of topical anesthetic to ensure comfort.
The waiting time depends on the area and the intensity level selected.

Application of the Fractional CO₂ Laser

The doctor passes the laser in consecutive lines or zones, evenly covering the chosen area.
The sensation is typically described as heat or small “pinpricks,” depending on the protocol.

Immediately after the treatment

Following the session, the skin may appear red and warm—normal reactions that gradually subside over the next hours.
A soothing application is provided at the clinic, and detailed aftercare instructions are given for the following days.

Session Duration

A session typically lasts 20–40 minutes, depending on the size of the area and the depth of treatment required.
Facial treatments are usually completed faster than treatments on larger body areas.

How Many Sessions Are Needed

The number of sessions depends on the severity of the concern and the degree of improvement the patient wishes to achieve.
Superficial imperfections may improve after a single session, while acne scars or deeper lines usually require a short protocol of repeated treatments.
The exact plan is determined following clinical evaluation.

Peeling & Recovery After Fractional CO₂ Laser

What to expect in the first days

Mild redness and a warm sensation are normal after the treatment and gradually fade.
Light peeling often appears—an expected sign of natural skin renewal.

Duration & aftercare

Peeling typically lasts 3–5 days.
Gentle skincare, good hydration and strict sun protection are recommended.

Return to daily activities

Most patients return to their routine immediately.
The intensity of reactions depends on the depth of treatment but remains predictable and manageable.

When are the results visible?

Initial results appear within 5–7 days, once the first renewal phase is complete.
More significant improvement becomes noticeable at 3–6 weeks, as the skin continues to remodel at deeper layers.
In multi-session protocols, results improve progressively after each treatment.

Fractional Laser – Before & After

Safety & Possible Side Effects


Fractional CO₂ Laser is a safe, controlled treatment when performed on suitable skin types and with the correct protocols.
Temporary sensitivity—such as redness or warmth—is expected and gradually subsides as the healing phase begins.
Correct adjustment of power, depth and coverage is essential to keep the treatment safe and predictable.

Dr. Makrygiorgis and the team at KM Plastic Surgery Clinic apply Fractional CO₂ Laser with customized protocols and precise mapping of the area, ensuring each treatment is adapted to the patient’s skin type and medical history.

For more information or to determine whether the treatment is right for you, you may contact the clinic here.

Together, we’ll discover the best version of yourself!

Book your appointment today!

Frequently Asked Questions (FAQs)

Is Fractional CO₂ Laser painful?

The treatment may create a sensation of warmth or light “pinpricks,” but a topical anesthetic is applied beforehand to make the experience as comfortable as possible.

What are the essential aftercare instructions?

Hydration, gentle cleansing and strict sun avoidance are required for at least 10–14 days after treatment.

Which is better for acne scars — mesotherapy or fractional laser?

For acne scars, Fractional CO₂ Laser is more effective because it acts deeper within the collagen matrix. Mesotherapy can be used as a complementary treatment.

Is it safe for all skin types?

Fractional CO₂ Laser is safe when performed on appropriate phototypes and with correct energy settings.
The doctor evaluates the skin to avoid unwanted reactions in more sensitive skin types.

Can Fractional Laser be done in the summer?

Yes, it can—but it requires strict sun avoidance and daily sunscreen.
For optimal control and safety, autumn–winter months are typically preferred.

What should I avoid after treatment?

For the first few days avoid:

  • strenuous exercise
  • makeup
  • direct sun exposure
  • sauna and intense heat

Your doctor will provide personalized aftercare instructions.

How does Fractional CO₂ differ from other lasers?

CO₂ lasers act deeper, targeting scars, wrinkles and photoaging that do not respond adequately to milder laser technologies.
Fractional delivery ensures faster recovery by treating only micro-columns of skin rather than the entire surface.