What is Hyaluronidase?<\/h2>\n\n\n\n
Hyaluronidase is an enzyme used for the targeted dissolution of hyaluronic acid from fillers.
It allows the doctor to remove or reduce unwanted product when complications or undesired outcomes occur, such as swelling, overcorrection, asymmetry or small nodules.<\/p>\n\n\n\n
How Does it Correct an Unsuccessful Filler?<\/h2>\n\n\n\n
Hyaluronidase is injected precisely into the area of concern, breaking down the hyaluronic acid so that the body can absorb it immediately.
Its action begins within a few minutes, while the final result stabilizes within 24\u201348 hours, offering fast and controlled correction.<\/p>\n\n\n\n
<\/p>\n\n\n\n
Results of Hyaluronidase<\/h2>\n\n\n\n
In most cases, results include:<\/p>\n\n\n\n
- \n
- visible reduction of swelling or volume<\/li>\n\n\n\n
- smoother texture<\/li>\n\n\n\n
- a more natural and balanced appearance<\/li>\n\n\n\n
- immediate relief from aesthetic imperfections caused by filler<\/li>\n<\/ul>\n\n\n\n
The area stabilizes quickly and, if needed, reassessment or a new filler treatment may follow.<\/p>\n<\/div>\n\n\n\n
\n![\"\"](\"https:\/\/makrygiorgisplasticsurgeon.com\/wp-content\/uploads\/2025\/12\/shutterstock_2478831041.jpg\")
<\/figure>\n<\/div>\n<\/div>\n\n\n\n<\/div>\n\n\n\nHyaluronidase for the Lips<\/h2>\n\n\n\n
Hyaluronidase for the lips is used when a lip filler does not achieve the desired outcome.
It can correct asymmetry, excess volume, firm lumps (nodules) or a \u201cheavy\u201d appearance due to improper technique or overfilling.
With targeted application, only the necessary amount of hyaluronic acid is dissolved, helping reduce swelling and restore the natural lip contour.
The procedure is short, virtually painless and provides fast improvement without affecting the surrounding tissues.<\/p>\n\n\n\n<\/div>\n\n\n\nHyaluronidase Under the Eyes<\/h2>\n\n\n\n
The under-eye area is particularly delicate, therefore fillers in this region may more easily lead to swelling, puffiness, bluish discoloration (Tyndall effect), or asymmetries.<\/p>\n\n\n\n
Hyaluronidase allows precise dissolution of the filler, reducing persistent swelling, improving the uniformity of the area and correcting filler that has migrated or been placed incorrectly.<\/p>\n\n\n\n
<\/div>\n\n\n\nLumps & Granulomas After Hyaluronic Acid Fillers<\/h2>\n\n\n\n
Lumps or small granulomas that may appear after fillers are usually due to overfilling, incorrect technique, or a tissue reaction.
Hyaluronidase is the most effective solution for their dissolution, as it acts locally and precisely.
The treatment is indicated when the issue does not resolve on its own or when it causes aesthetic concern.<\/p>\n\n\n\n<\/div>\n\n\n\n\n\n\n![](\"https:\/\/makrygiorgisplasticsurgeon.com\/wp-content\/uploads\/2025\/03\/image00158.webp\")
\n<\/div>\n\n\n\n\nPlastic Surgeon Dr. Konstantinos Ch. Makrygiorgis<\/strong><\/h4>\n\n\n\n
Plastic surgery is the perfect blend of science and art<\/strong>, of passion and technology<\/strong>. Our primary goal is to help you achieve your personal aesthetic aspirations, while also providing you with clear and honest guidance for your benefit. Perfectionists by nature, we are fully committed to your vision to how you<\/strong> imagine your best self. Because perfection is a deeply personal matter<\/strong>, and it doesn’t come in one single form.<\/p>\n\n\n\nLearn more about the Doctor<\/a>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
<\/div>\n\n\n\nHyaluronic Acid Dissolution \u2013 Step by Step<\/h2>\n\n\n\n
The hyaluronidase procedure is short, targeted and tailored to each patient\u2019s needs. The goal is to dissolve exactly the amount of hyaluronic acid required, without affecting the surrounding tissues.<\/p>\n\n\n\n
The main steps include:<\/p>\n\n\n\n
Clinical evaluation of the area<\/strong><\/p>\n\n\n\n
The doctor examines the area, identifies the issue and determines the correct dose of hyaluronidase.<\/p>\n\n\n\n
Topical anesthesia (if needed)<\/strong><\/p>\n\n\n\n
A topical anesthetic cream may be applied for greater comfort.<\/p>\n\n\n\n
Targeted hyaluronidase injection<\/strong><\/p>\n\n\n\n
The enzyme is injected only in the areas that require correction to ensure precise dissolution.<\/p>\n\n\n\n
Immediate observation of the effect<\/strong><\/p>\n\n\n\n
Initial improvement is often visible within the first few minutes.<\/p>\n\n\n\n
Post-treatment instructions<\/strong><\/p>\n\n\n\n
Avoid applying strong pressure to the area and apply ice if mild swelling occurs.<\/p>\n\n\n\n
<\/div>\n\n\n\nIs the procedure safe?<\/h2>\n\n\n\n
Hyaluronidase is generally considered a safe and well-tolerated treatment when performed by a qualified medical professional.
Side effects are usually mild and temporary, limited to the injection site.<\/p>\n\n\n\nPossible side effects include:<\/p>\n\n\n\n
- \n
- slight redness or tenderness<\/li>\n\n\n\n
- minor swelling that resolves quickly<\/li>\n\n\n\n
- temporary burning sensation<\/li>\n<\/ul>\n\n\n\n<\/div>\n\n\n\n
Hyaluronidase & Allergy \u2013 How likely is it?<\/h2>\n\n\n\n
Allergic reactions are extremely rare. The doctor evaluates the patient\u2019s medical history and performs the treatment with full safety precautions.
In the unlikely event of a strong hypersensitivity reaction, immediate medical management is available at the clinic.<\/p>\n\n\n\n<\/div>\n\n\n\nWhy expertise matters<\/h2>\n\n\n\n
Hyaluronidase application requires precision, experience and a thorough understanding of how fillers behave within the tissues.
Dr. Makrygiorgis and his team at KM Plastic Surgery Clinic have extensive experience in correcting fillers in the lips, under-eye area and face, managing cases that require targeted and controlled filler dissolution.
For accurate information and personalized cost assessment:<\/p>\n\n\n\n
\u2192 Contact us here<\/a><\/p>\n\n\n\n